A cell is the smallest structural and functional unit of an organism. A cell is typically microscopic and consists of cytoplasm, a nucleus and enclosed in a membrane. For the information, a cell also has reproduction same like human, animal and plant. Due to Rudolf Virchow (1855), a German physician said that “Where a cell exists, there must have been a pre-existing cell, just as the animal arises only from an animal and the plant only from a plant”. He can be concluded that this concept with the Latin axiom “Omnis cellula e cellula,” that means “Every cell from a cell”. It shows that the continuing life of the cell by doing the cell reproduction. To make the cell do the reproduction, the cell must have to do the division. To make the
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The first stage of mitosis is prophase. The centrosomes will move to the opposite sides of the nucleus. Formation of the mitotic chromosome the nucleus of an Interphase cell contains tremendous lengths of chromatin fibers spread throughout the entire nuclear compartment. After that, the chromatin fibers will become more tightly coiled, condensing into discrete chromosomes observed with a light microscope. Chromosomes, a cell converts them into shorter, thicker fibers by a process of chromosome compaction, which occurs during early prophase. Then, the nucleus will disappear and mitotic spindle will begin to form and complete at the end of this stage. According to McIntosh and McDonald (1989), the mitotic spindle is a bipolar, self-organizing microtubule (MT)-based machine that uses energy liberated from nucleotide hydrolysis to segregate sister chromatids accurately into the daughter cells during cell division. But, differently with the plant which it will not appear centrioles when the spindle forms.
After that, the chromosomes start to move towards the center of the nucleus and it ended with the breakdown and also the nuclear envelope will disappear. For each duplicated chromosome appears as two identical sister chromatids and joined at their centromeres along with their arms by sister chromatid cohesion. It stated that the cohesion is important for the pairwise alignment of